Compound Detail
CHEMBL2441069
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Basic Information
| ChEMBL ID | CHEMBL2441069 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HGEYPDAIHVMWBT-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
303.2
MW (Da)
1.67
ALogP
3
HBA
1
HBD
49.4
PSA (Ų)
0.86
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.32
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor 2 CHEMBL3503 | EC50 | 5.32 | 5.32 | 4830.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor 2 | EC50 | = | 4830.0 | nM | 5.32 | Positive allosteric modulation of GluA2 receptor in rat embryonic cortex neuron ... | 24131202 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24131202 | 10.1021/jm4012092 | Glutamate receptor 2 | 3 |
Data from ChEMBL 36 via Core Engine