Compound Detail
CHEMBL2443109
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL2443109 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CTRYLWXDLBCDMT-BAUSSPIASA-N |
| Parent Compound | CHEMBL3040754 |
| Active Moiety | CHEMBL3040754 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
191.2
MW (Da)
0.04
ALogP
3
HBA
2
HBD
63.3
PSA (Ų)
0.57
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Bacterial leucyl aminopeptidase CHEMBL3750 | Ki | 5.4 | 5.4 | 4000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Bacterial leucyl aminopeptidase | Ki | = | 4000.0 | nM | 5.4 | Inhibition of Aeromonas proteolytica leucyl aminopeptidase using L-leucine para-... | 24055078 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24055078 | 10.1016/j.bmc.2013.08.044 | Bacterial leucyl aminopeptidase | 1 |
| 24055078 | 10.1016/j.bmc.2013.08.044 | Aminopeptidase N | 1 |
Data from ChEMBL 36 via Core Engine