Compound Detail
CHEMBL2443112
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Basic Information
| ChEMBL ID | CHEMBL2443112 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LIYHDAUQJYMJMP-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
429.5
MW (Da)
5.22
ALogP
3
HBA
0
HBD
36.4
PSA (Ų)
0.57
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.6
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Egl nine homolog 1 CHEMBL5697 | IC50 | 7.6 | 7.6 | 25.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Egl nine homolog 1 | IC50 | = | 25.12 | nM | 7.6 | Inhibition of PHD2 (unknown origin) by HTRF assay | 24055079 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24055079 | 10.1016/j.bmc.2013.08.046 | Egl nine homolog 1 | 1 |
Data from ChEMBL 36 via Core Engine