Compound Detail
CHEMBL246790
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Basic Information
| ChEMBL ID | CHEMBL246790 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ROYXKWFBXGVHOV-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
447.5
MW (Da)
5.61
ALogP
5
HBA
2
HBD
72.1
PSA (Ų)
0.45
QED
1
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Melanin-concentrating hormone receptor 1 CHEMBL344 | Ki | 7.0 | 7.0 | 101.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Melanin-concentrating hormone receptor 1 | Ki | = | 101.0 | nM | 7.0 | Displacement of [125I][Phe13, Tyr19]MCH from human recombinant MCHR1 expressed i... | 17448659 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17448659 | 10.1016/j.bmcl.2007.04.012 | Melanin-concentrating hormone receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine