Compound Detail
CHEMBL247719
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL247719 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | QAQMSWWMDJCGEW-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
450.6
MW (Da)
5.59
ALogP
5
HBA
1
HBD
75.8
PSA (Ų)
0.37
QED
1
Ro5 Violations
13
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.75
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor gamma CHEMBL235 | EC50 | 5.75 | 5.75 | 1800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Peroxisome proliferator-activated receptor gamma | EC50 | = | 1800.0 | nM | 5.75 | Agonist activity at PPARgamma receptor expressed in HEK293 cells by GAL4 transac... | 17292606 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 17292606 | 10.1016/j.bmcl.2007.01.060 | Peroxisome proliferator-activated receptor gamma | 4 |
| 17292606 | 10.1016/j.bmcl.2007.01.060 | Peroxisome proliferator-activated receptor alpha | 2 |
Data from ChEMBL 36 via Core Engine