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Compound Detail

CHEMBL253510

TETRAHYDRO-8-HYDROXYMANZAMINE A
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Oc1cccc2c1[nH]c1c(C3=C[C@@]4(O)CCCCCCCCN5CCC3[C@]3(C[C@@H]6CCCCCCN6[C@H]34)C5)nccc12
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL253510
Name TETRAHYDRO-8-HYDROXYMANZAMINE A
Phase Preclinical
Structure Type MOL
InChI Key BHRFYFSYVSXAIC-JDHRKNKSSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

568.8
MW (Da)
7.01
ALogP
5
HBA
3
HBD
75.6
PSA (Ų)
0.29
QED
2
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C36H48N4O2
MW 568.81
Aromatic Rings 3
Heavy Atoms 42
NP-Likeness 1.87

Literature References

PubMed DOI Target Context # Activities
17708655 10.1021/np060092r Glycogen synthase kinase-3 beta 2

Data from ChEMBL 36 via Core Engine