Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL259564

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
CC1(C)CC(=O)C(C(=O)Nc2cccc(C(F)(F)F)c2)C(=O)C1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL259564
Phase Preclinical
Structure Type MOL
InChI Key SHFUWUPRZXSPJS-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

327.3
MW (Da)
3.22
ALogP
3
HBA
1
HBD
63.2
PSA (Ų)
0.85
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C16H16F3NO3
MW 327.30
Aromatic Rings 1
Heavy Atoms 23
NP-Likeness -1.07

Literature References

PubMed DOI Target Context # Activities
18226531 10.1016/j.bmc.2007.12.031 Potassium voltage-gated channel subfamily A member 1 2
18226531 10.1016/j.bmc.2007.12.031 Voltage-gated potassium channel subfamily A member 1/beta-1 1
18226531 10.1016/j.bmc.2007.12.031 Potassium voltage-gated channel subfamily A member 4 1
18226531 10.1016/j.bmc.2007.12.031 A-type voltage-gated potassium channel KCND2 1
18226531 10.1016/j.bmc.2007.12.031 Mus musculus 1

Data from ChEMBL 36 via Core Engine