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Compound Detail

CHEMBL259773

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Nc1ncnc2c1ncn2[C@@H]1C[C@H](F)[C@@H](O)[C@H]1O
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL259773
Phase Preclinical
Structure Type MOL
InChI Key AHYAHCRLJXRKDN-LAHCRNKXSA-N
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
7
Publications
0
Known Names

Molecular Properties

253.2
MW (Da)
-0.59
ALogP
7
HBA
3
HBD
110.1
PSA (Ų)
0.63
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C10H12FN5O2
MW 253.24
Aromatic Rings 2
Heavy Atoms 18
NP-Likeness 0.39

Activity Summary

IC50 1 meas.

Literature References

PubMed DOI Target Context # Activities
18374570 10.1016/j.bmcl.2008.03.029 Adenosylhomocysteinase 2
19329326 10.1016/j.bmc.2009.03.004 Measles morbillivirus 2
18374570 10.1016/j.bmcl.2008.03.029 Unchecked 1
19329326 10.1016/j.bmc.2009.03.004 ADMET 1
19329326 10.1016/j.bmc.2009.03.004 Cytomegalovirus 1
19329326 10.1016/j.bmc.2009.03.004 Vaccinia virus 1
19329326 10.1016/j.bmc.2009.03.004 Cowpox virus 1

Data from ChEMBL 36 via Core Engine