Compound Detail
CHEMBL262382
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CSCC[C@H]1NC(=O)[C@H](Cc2ccc(OP(=O)(O)O)cc2)NC(=O)[C@@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@@H](N)CCC(=O)O)CCCCNC(=O)NCC(=O)C[C@H](C(=O)N[C@@H](CC(C)C)C(=O)O)NC1=O
Basic Information
| ChEMBL ID | CHEMBL262382 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AKLCVXCYGSJXAW-MJVVSAGYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
1087.2
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 6.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tyrosine-protein phosphatase non-receptor type 6 CHEMBL3166 | Kd | 6.96 | 6.96 | 110.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tyrosine-protein phosphatase non-receptor type 6 | Kd | = | 110.0 | nM | 6.96 | Dissociation constant for the interaction with the GST-N-SH2 domain of SHP-1 | 15743195 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15743195 | 10.1021/jm049151t | Tyrosine-protein phosphatase non-receptor type 6 | 2 |
Data from ChEMBL 36 via Core Engine