Compound Detail
CHEMBL263327
(PHENYLSULFONYL)BENZENE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL263327 |
| Name | (PHENYLSULFONYL)BENZENE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KZTYYGOKRVBIMI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
218.3
MW (Da)
2.52
ALogP
2
HBA
0
HBD
34.1
PSA (Ų)
0.78
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 6 CHEMBL3371 | Ki | 5.8 | 5.8 | 1598.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 6 | Ki | = | 1598.0 | nM | 5.8 | Antagonist activity at recombinant human 5-HT6 receptor expressed in HEK293 cell... | 23787290 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18558667 | 10.1021/jm701549s | No relevant target | 2 |
| 15857133 | 10.1021/jm048980b | No relevant target | 1 |
| 17311370 | 10.1021/jm060706p | Cytochrome P450 2C9 | 1 |
| 23787290 | 10.1016/j.bmc.2013.05.040 | 5-hydroxytryptamine receptor 6 | 1 |
Data from ChEMBL 36 via Core Engine