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Compound Detail

CHEMBL265763

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NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccc2ccc(OCc3ccccc3)cc2c1)[C@H](O)C(=O)NO

Basic Information

ChEMBL ID CHEMBL265763
Phase Preclinical
Structure Type MOL
InChI Key GNWXHESPUNJCNK-PKTNWEFCSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

541.6
MW (Da)
2.66
ALogP
6
HBA
5
HBD
151.0
PSA (Ų)
0.14
QED
1
Ro5 Violations
12
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C31H31N3O6
MW 541.60
Aromatic Rings 4
Heavy Atoms 40
NP-Likeness -0.01

Literature References

PubMed DOI Target Context # Activities
10560745 10.1016/s0960-894x(99)00552-1 Low affinity immunoglobulin epsilon Fc receptor 1
10560745 10.1016/s0960-894x(99)00552-1 Interstitial collagenase 1

Data from ChEMBL 36 via Core Engine