Compound Detail
CHEMBL268205
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC(C)NCc1ccc(C[C@@H]2NC(=O)[C@H](Cc3c[nH]c4ccccc34)NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](Cc3ccccc3)NC(=O)[C@@H](CCCCN)NC(=O)[C@H](N)CSSC[C@@H](C(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H]([C@@H](C)O)NC(=O)[C@H](Cc3ccc(O)cc3)NC(=O)[C@@H]([C@@H](C)O)NC2=O)cc1
Basic Information
| ChEMBL ID | CHEMBL268205 |
| Phase | Preclinical |
| Structure Type | BOTH |
| InChI Key | FJRAPOZDHJLSPN-HXVVHKOFSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
1501.8
MW (Da)
Drug Information
| Molecule Type | Protein |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.77
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Somatostatin receptor type 1 CHEMBL1917 | IC50 | 7.77 | 7.77 | 17.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Somatostatin receptor type 1 | IC50 | = | 17.0 | nM | 7.77 | Inhibition of [Leu8,D-Trp22,125I-Tyr25]SRIF-28 binding to human somatostatin rec... | 15658864 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15658864 | 10.1021/jm049520l | Somatostatin receptor type 1 | 1 |
| 15658864 | 10.1021/jm049520l | Somatostatin receptor type 2 | 1 |
| 15658864 | 10.1021/jm049520l | Somatostatin receptor type 3 | 1 |
| 15658864 | 10.1021/jm049520l | Somatostatin receptor type 4 | 1 |
| 15658864 | 10.1021/jm049520l | Somatostatin receptor type 5 | 1 |
Data from ChEMBL 36 via Core Engine