Compound Detail

CHEMBL268291

DIMETHYLFORMAMIDE

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CN(C)C=O

ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID	CHEMBL268291
Name	DIMETHYLFORMAMIDE
Phase	Preclinical
Structure Type	MOL
InChI Key	ZMXDDKWLCZADIW-UHFFFAOYSA-N

Targets

Activities

Assay Types

PK Parameters

Publications

Known Names

73.1

MW (Da)

-0.30

ALogP

HBA

HBD

20.3

PSA (Å²)

0.39

QED

Ro5 Violations

Rot. Bonds

Natural Product First in Class Prodrug

EC50 1 meas.

PubMed	DOI	Target Context	# Activities
-	10.6019/CHEMBL3885881	Rattus norvegicus	1265
27316545	10.1016/j.bmc.2016.05.056	Nuclear factor erythroid 2-related factor 2	7
30196061	10.1016/j.ejmech.2018.08.071	Nuclear factor erythroid 2-related factor 2	6
3712373	10.1021/jm00156a024	Mus musculus	5
17959273	10.1016/j.ejmech.2007.08.007	Escherichia coli	3
17959273	10.1016/j.ejmech.2007.08.007	Bacillus	3
17959273	10.1016/j.ejmech.2007.08.007	Aspergillus niger	3
27316545	10.1016/j.bmc.2016.05.056	ADMET	3
17959273	10.1016/j.ejmech.2007.08.007	Macrophomina phaseolina	3
27316545	10.1016/j.bmc.2016.05.056	NON-PROTEIN TARGET	3
19896248	10.1016/j.ejmech.2009.10.001	Staphylococcus capitis	2
34252790	10.1016/j.bmc.2021.116300	Nuclear factor erythroid 2-related factor 2	2
-	10.1007/s00044-007-9047-2	Escherichia coli	2
-	10.1007/s00044-007-9047-2	Pseudomonas aeruginosa	2
-	10.1007/s00044-007-9047-2	Bacillus subtilis	2
-	10.1007/s00044-007-9047-2	Staphylococcus aureus	2
-	10.1007/s00044-007-9047-2	Aspergillus niger	1
24486419	10.1016/j.ejmech.2013.12.055	NON-PROTEIN TARGET	1
-	10.1007/s00044-007-9047-2	Fusarium oxysporum	1
20553011	10.1021/tx1000865	Hepatotoxicity	1

Data from ChEMBL 36 via Core Engine