Compound Detail
CHEMBL269181
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CC(C)C(NC(=O)Cn1c(-c2ccc(F)cc2)ncc(N)c1=O)B1OC(C)(C)C(C)(C)O1
Basic Information
| ChEMBL ID | CHEMBL269181 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VXLYNXXMTFPZRH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
444.3
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Neutrophil elastase CHEMBL248 | Ki | 8.21 | 8.21 | 6.2 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Neutrophil elastase | Ki | = | 6.2 | nM | 8.21 | In vitro inhibition of human leukocyte elastase mediated hydrolysis of the synth... | 7837246 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 7837246 | 10.1021/jm00001a015 | Cricetinae gen. sp. | 3 |
| 7837246 | 10.1021/jm00001a015 | Neutrophil elastase | 1 |
Data from ChEMBL 36 via Core Engine