Compound Detail
CHEMBL270495
TRIPHENYLACETIC ACID METHYL ESTER Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL270495 |
| Name | TRIPHENYLACETIC ACID METHYL ESTER |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZPGOQUZHRVSLML-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
302.4
MW (Da)
4.19
ALogP
2
HBA
0
HBD
26.3
PSA (Ų)
0.53
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.48
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Intermediate conductance calcium-activated potassium channel protein 4 CHEMBL4305 | IC50 | 6.48 | 6.48 | 330.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Intermediate conductance calcium-activated potassium channel protein 4 | IC50 | = | 330.0 | nM | 6.48 | Inhibition of Gardos channel in human RBC assessed as inhibition of ionomycin-st... | 18232633 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18232633 | 10.1021/jm070663s | Intermediate conductance calcium-activated potassium channel protein 4 | 1 |
Data from ChEMBL 36 via Core Engine