Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL271414

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
COc1cc2nccc(N(C)c3ccc4c(C(=O)Nc5ccc(Cl)cc5)cccc4c3)c2cc1OC
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL271414
Phase Preclinical
Structure Type MOL
InChI Key XGTBKSVZQRIRGR-UHFFFAOYSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

498.0
MW (Da)
7.08
ALogP
5
HBA
1
HBD
63.7
PSA (Ų)
0.27
QED
1
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C29H24ClN3O3
MW 497.98
Aromatic Rings 5
Heavy Atoms 36
NP-Likeness -1.06

Literature References

PubMed DOI Target Context # Activities
18324761 10.1021/jm701097z HUVEC 2
18324761 10.1021/jm701097z Vascular endothelial growth factor receptor 2 1

Data from ChEMBL 36 via Core Engine