Compound Detail
CHEMBL271966
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Basic Information
| ChEMBL ID | CHEMBL271966 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | USRFZFJWORLWQN-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
1
PK Parameters
3
Publications
0
Known Names
Molecular Properties
544.7
MW (Da)
3.94
ALogP
9
HBA
3
HBD
98.9
PSA (Ų)
0.23
QED
1
Ro5 Violations
12
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 9.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Respiratory syncytial virus CHEMBL612679 | EC50 | 9.3 | 9.3 | 0.5 | 1 |
Pharmacokinetic Data
| Parameter | Value | Units | Species |
|---|---|---|---|
| t1/2 | - | - | Rattus norvegicus |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Respiratory syncytial virus | EC50 | = | 0.5012 | nM | 9.3 | Inhibition of RSV by MTT assay | 18254606 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18254606 | 10.1021/jm701284j | Rattus norvegicus | 1 |
| 18254606 | 10.1021/jm701284j | Respiratory syncytial virus | 1 |
| 18254606 | 10.1021/jm701284j | NON-PROTEIN TARGET | 1 |
Data from ChEMBL 36 via Core Engine