Compound Detail
CHEMBL272335
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CSCC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCC(N)=O)NC(=O)CCCCCCCNC(=O)CCCCCN)C(C)C)C(N)=O
Basic Information
| ChEMBL ID | CHEMBL272335 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IHQBXPLXVIPJRV-WPVZLMRRSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
1194.5
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 9.43
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Gastrin-releasing peptide receptor CHEMBL4959 | EC50 | 9.43 | 9.43 | 0.4 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Gastrin-releasing peptide receptor | EC50 | = | 0.373 | nM | 9.43 | Displacement of 125I[Tyr4]-bombesin from GRPR expressed in human PC3 cells | 18329268 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18329268 | 10.1016/j.bmcl.2008.02.051 | Gastrin-releasing peptide receptor | 1 |
Data from ChEMBL 36 via Core Engine