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Compound Detail

CHEMBL272757

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O=C1NC(=O)C(=Cc2ccccc2)C(=O)N1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL272757
Phase Preclinical
Structure Type MOL
InChI Key CMWDWOZYVQQAMI-UHFFFAOYSA-N
0
Targets
2
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names

Molecular Properties

216.2
MW (Da)
0.44
ALogP
3
HBA
2
HBD
75.3
PSA (Ų)
0.53
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C11H8N2O3
MW 216.20
Aromatic Rings 1
Heavy Atoms 16
NP-Likeness -0.49

Activity Summary

Ki 2 meas.

Literature References

PubMed DOI Target Context # Activities
18343108 10.1016/j.bmcl.2008.02.066 Unchecked 1
18343108 10.1016/j.bmcl.2008.02.066 Methionine aminopeptidase 1 1
19904929 10.1021/jm901183d RAW264.7 1
24361188 10.1016/j.bmc.2013.12.010 Nakaseomyces glabratus 1
24361188 10.1016/j.bmc.2013.12.010 Candida albicans 1

Data from ChEMBL 36 via Core Engine