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Compound Detail

CHEMBL274239

TIARAMIDE
🧪 Phase II
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🧪 Phase II
O=C(Cn1c(=O)sc2ccc(Cl)cc21)N1CCN(CCO)CC1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL274239
Name TIARAMIDE
Phase Phase II
Structure Type MOL
InChI Key HTJXMOGUGMSZOG-UHFFFAOYSA-N

Known Names

RHC 2592A RHC-2592A Tialamide Tiaramida Tiaramide
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
11
Publications
5
Known Names

Molecular Properties

355.9
MW (Da)
0.85
ALogP
6
HBA
1
HBD
65.8
PSA (Ų)
0.88
QED
0
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Chirality Achiral
USAN Year 1981

Extended Properties

Molecular Formula C15H18ClN3O3S
MW 355.85
Aromatic Rings 2
Heavy Atoms 23
NP-Likeness -2.11

Literature References

PubMed DOI Target Context # Activities
1552506 10.1021/jm00084a019 Rattus norvegicus 21
15646539 10.1016/s0399-8320(04)95062-2 Unchecked 11
15646539 10.1016/s0399-8320(04)95062-2 NON-PROTEIN TARGET 8
3491209 10.1021/jm00161a026 Rattus norvegicus 5
3491209 10.1021/jm00161a026 Mus musculus 2
- 10.6019/CHEMBL4495565 SARS-CoV-2 2
- 10.6019/CHEMBL4651402 SARS-CoV-2 2
- 10.6019/CHEMBL4808148 Histone deacetylase 6 2
20020916 10.1080/15376510701857262 Phospholipidosis 1
- 10.21203/rs.3.rs-23951/v1 SARS-CoV-2 1
- 10.6019/CHEMBL4495564 Replicase polyprotein 1ab 1

Data from ChEMBL 36 via Core Engine