Compound Detail
CHEMBL275098
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Basic Information
| ChEMBL ID | CHEMBL275098 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DJXNJVFEFSWHLY-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
8
Publications
0
Known Names
Molecular Properties
173.2
MW (Da)
1.93
ALogP
2
HBA
1
HBD
50.2
PSA (Ų)
0.72
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.2
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Maltase-glucoamylase CHEMBL2074 | IC50 | 4.2 | 4.2 | 63000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Maltase-glucoamylase | IC50 | = | 63000.0 | nM | 4.2 | Inhibition of alpha-glucosidase (unknown origin) | 38508120 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 109613 | 10.1021/jm00193a013 | Rattus norvegicus | 2 |
| 24499135 | 10.1021/jm401808n | Staphylococcus aureus | 2 |
| 6127411 | 10.1021/jm00351a015 | GABA-A receptor; anion channel | 1 |
| 17154519 | 10.1021/jm060601m | Histone acetyltransferase GCN5 | 1 |
| 24499135 | 10.1021/jm401808n | Quinolone resistance protein NorA | 1 |
| 26492576 | 10.1021/acs.jmedchem.5b01114 | Glycogen phosphorylase, muscle form | 1 |
| 30579791 | 10.1016/j.bmcl.2018.12.027 | Human immunodeficiency virus type 1 reverse transcriptase | 1 |
| 38508120 | 10.1016/j.ejmech.2024.116332 | Maltase-glucoamylase | 1 |
Data from ChEMBL 36 via Core Engine