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Compound Detail

CHEMBL27577

SALICYLAMIDE
🧪 Phase II
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🧪 Phase II
NC(=O)c1ccccc1O
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL27577
Name SALICYLAMIDE
Phase Phase II
Structure Type MOL
InChI Key SKZKKFZAGNVIMN-UHFFFAOYSA-N

Known Names

NSC-3115 Salicilamida Salicylamide
0
Targets
4
Activities
1
Assay Types
0
PK Parameters
20
Publications
3
Known Names
2
Indications

Molecular Properties

137.1
MW (Da)
0.49
ALogP
2
HBA
2
HBD
63.3
PSA (Ų)
0.59
QED
0
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Chirality Achiral

Flags

Natural Product
USAN Stem sal-

Extended Properties

Molecular Formula C7H7NO2
MW 137.14
Aromatic Rings 1
Heavy Atoms 10
NP-Likeness -0.21

Indications

Fever Pain

ATC Classification

N02BA05
salicylamide
Level 1: NERVOUS SYSTEM
Level 2: ANALGESICS
N02BA55
salicylamide, combinations excl. psycholeptics
Level 1: NERVOUS SYSTEM
Level 2: ANALGESICS
N02BA75
salicylamide, combinations with psycholeptics
Level 1: NERVOUS SYSTEM
Level 2: ANALGESICS

Activity Summary

EC50 4 meas.

Literature References

PubMed DOI Target Context # Activities
- 10.6019/CHEMBL3885881 Rattus norvegicus 273
19223628 10.1128/aac.01293-08 Staphylococcus aureus 4
30568753 10.1039/C8MD00436F Unchecked 3
20014752 10.1021/tx900326k Hepatotoxicity 3
22154834 10.1016/j.ejmech.2011.11.030 Unchecked 2
9083482 10.1021/jm960755+ Human immunodeficiency virus type 1 integrase 2
15509168 10.1021/jm0495226 Androgen receptor 2
17889969 10.1016/j.ejmech.2007.07.018 Mus musculus 2
- 10.6019/CHEMBL4651402 SARS-CoV-2 2
14613328 10.1021/jm0303305 Androgen receptor 2
- 10.6019/CHEMBL4495565 SARS-CoV-2 2
- 10.6019/CHEMBL4808148 Histone deacetylase 6 2
21189019 10.1021/jm101266s Neutrophil collagenase 1
21189019 10.1021/jm101266s Tyrosinase 1
21189019 10.1021/jm101266s Interstitial collagenase 1
21189019 10.1021/jm101266s Lethal factor 1
21189019 10.1021/jm101266s 72 kDa type IV collagenase 1
21145740 10.1016/j.bmcl.2010.11.060 Rho-associated protein kinase 1 1
17827020 10.1016/j.bmc.2007.07.050 Skin 1
12477346 10.1021/jm020160g Stromelysin-1 1

Data from ChEMBL 36 via Core Engine