Compound Detail
CHEMBL278081
HISTIDINOL Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL278081 |
| Name | HISTIDINOL |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZQISRDCJNBUVMM-YFKPBYRVSA-N |
1
Targets
2
Activities
2
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
141.2
MW (Da)
-0.73
ALogP
3
HBA
3
HBD
74.9
PSA (Ų)
0.52
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 10.46
Ki 1 meas.
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Olfactory receptor 51E2 CHEMBL4523454 | EC50 | 10.46 | 10.46 | 0.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Olfactory receptor 51E2 | EC50 | = | 0.035 | nM | 10.46 | Agonist activity at PSGR/OR51E2 (unknown origin) expressed in human Hana3A cells... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10197963 | 10.1021/jm980408v | Histamine H3 receptor | 1 |
| 17481905 | 10.1016/j.bmc.2007.04.027 | Histidinol dehydrogenase | 1 |
Data from ChEMBL 36 via Core Engine