Compound Detail
CHEMBL279907
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Basic Information
| ChEMBL ID | CHEMBL279907 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WSNDRKOLHPSTJY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
309.2
MW (Da)
4.47
ALogP
2
HBA
0
HBD
16.1
PSA (Ų)
0.81
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.37
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histamine H1 receptor CHEMBL3943 | IC50 | 6.37 | 6.37 | 430.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Histamine H1 receptor | IC50 | = | 430.0 | nM | 6.37 | Inhibition of [3H]mepyramine binding to the Histamine H1 receptor in guinea pig ... | 1673158 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1673158 | 10.1021/jm00108a012 | Cavia porcellus | 1 |
| 1673158 | 10.1021/jm00108a012 | Histamine H1 receptor | 1 |
Data from ChEMBL 36 via Core Engine