Compound Detail
CHEMBL286394
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Basic Information
| ChEMBL ID | CHEMBL286394 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FVAAHBHWXQJFLG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
362.2
MW (Da)
5.12
ALogP
4
HBA
1
HBD
65.8
PSA (Ų)
0.70
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 1-acyl-sn-glycerol-3-phosphate acyltransferase beta CHEMBL4772 | IC50 | 7.82 | 7.82 | 15.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 1-acyl-sn-glycerol-3-phosphate acyltransferase beta | IC50 | = | 15.0 | nM | 7.82 | Inhibitory concentration against human lysophosphatidic acid acyltransferase-bet... | 15006381 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15006381 | 10.1016/j.bmcl.2004.01.023 | 1-acyl-sn-glycerol-3-phosphate acyltransferase beta | 1 |
| 15006381 | 10.1016/j.bmcl.2004.01.023 | 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha | 1 |
Data from ChEMBL 36 via Core Engine