Compound Detail
CHEMBL28837
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Basic Information
| ChEMBL ID | CHEMBL28837 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | SJIRXOAJZXJAKQ-MOPGFXCFSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
370.5
MW (Da)
4.54
ALogP
5
HBA
1
HBD
72.8
PSA (Ų)
0.32
QED
0
Ro5 Violations
16
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.83
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Protein kinase C alpha type CHEMBL2855 | Ki | 5.83 | 5.83 | 1470.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Protein kinase C alpha type | Ki | = | 1470.0 | nM | 5.83 | Inhibition of [3H]PDBU binding to Protein kinase C alpha | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/S0960-894X(01)80364-4 | Protein kinase C (PKC) | 1 |
| - | 10.1016/S0960-894X(01)80364-4 | Protein kinase C alpha type | 1 |
Data from ChEMBL 36 via Core Engine