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Compound Detail

CHEMBL291747

THREONINE
🧪 Phase II
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🧪 Phase II
C[C@@H](O)[C@H](N)C(=O)O

Basic Information

ChEMBL ID CHEMBL291747
Name THREONINE
Phase Phase II
Structure Type MOL
InChI Key AYFVYJQAPQTCCC-GBXIJSLDSA-N

Known Names

FEMA NO. 4710 L-threonine NSC-16589 NSC-46701 Threonine Treonina
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
20
Publications
6
Known Names

Molecular Properties

119.1
MW (Da)
-1.22
ALogP
3
HBA
3
HBD
83.5
PSA (Ų)
0.43
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Chirality Single Enantiomer

Flags

Natural Product
USAN Year 1979

Extended Properties

Molecular Formula C4H9NO3
MW 119.12
Aromatic Rings 0
Heavy Atoms 8
NP-Likeness 1.17

Literature References

PubMed DOI Target Context # Activities
- 10.6019/CHEMBL4808148 Histone deacetylase 6 2
37468498 10.1038/s41467-023-40064-9 Thromboxane A2 receptor 2
37468498 10.1038/s41467-023-40064-9 Prostaglandin G/H synthase 1 2
37468498 10.1038/s41467-023-40064-9 Alpha-1A adrenergic receptor 2
- 10.6019/CHEMBL4651402 SARS-CoV-2 2
- 10.6019/CHEMBL4495565 SARS-CoV-2 2
37468498 10.1038/s41467-023-40064-9 Muscarinic acetylcholine receptor M1 2
- 10.6019/CHEMBL4495564 Replicase polyprotein 1ab 1
814238 10.1021/jm00224a031 No relevant target 1
11278508 10.1074/jbc.m009462200 Monocarboxylate transporter 10 1
3656360 10.1021/jm00393a031 Unchecked 1
34726055 10.1021/acs.jmedchem.1c00981 Pyruvate kinase PKM 1
37468498 10.1038/s41467-023-40064-9 D(1A) dopamine receptor 1
37468498 10.1038/s41467-023-40064-9 Voltage-gated inwardly rectifying potassium channel KCNH2 1
37468498 10.1038/s41467-023-40064-9 Sodium-dependent dopamine transporter 1
37468498 10.1038/s41467-023-40064-9 Estrogen receptor 1
19060912 10.1038/nchembio.132 General amino-acid permease GAP1 1
37468498 10.1038/s41467-023-40064-9 Sodium-dependent noradrenaline transporter 1
37468498 10.1038/s41467-023-40064-9 Sodium-dependent serotonin transporter 1
10450958 10.1016/s0960-894x(99)00297-8 Unchecked 1

Data from ChEMBL 36 via Core Engine