Compound Detail
CHEMBL295830
CYCLOLEUCINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL295830 |
| Name | CYCLOLEUCINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | NILQLFBWTXNUOE-UHFFFAOYSA-N |
0
Targets
6
Activities
2
Assay Types
0
PK Parameters
19
Publications
0
Known Names
Molecular Properties
129.2
MW (Da)
0.34
ALogP
2
HBA
2
HBD
63.3
PSA (Ų)
0.54
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 4 meas.
Ki 2 meas.
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 69024 | 10.1021/jm00216a001 | Trypanosoma cruzi | 3 |
| 35796517 | 10.1021/acs.jmedchem.2c00395 | S-adenosylmethionine synthase isoform type-2 | 2 |
| 35796517 | 10.1021/acs.jmedchem.2c00395 | Unchecked | 2 |
| - | 10.6019/CHEMBL4651402 | SARS-CoV-2 | 2 |
| 814238 | 10.1021/jm00224a031 | Jensen sarcoma | 2 |
| 137981 | 10.1021/jm00212a010 | Plasmodium berghei | 2 |
| 137981 | 10.1021/jm00212a010 | Enterococcus faecium | 2 |
| 137981 | 10.1021/jm00212a010 | Lacticaseibacillus casei | 2 |
| 137981 | 10.1021/jm00212a010 | NON-PROTEIN TARGET | 2 |
| 38318365 | 10.1016/j.isci.2024.108907 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 1 |
| 9873403 | 10.1016/s0960-894x(98)00267-4 | S-adenosylmethionine synthase isoform type-1 | 1 |
| 137981 | 10.1021/jm00212a010 | Escherichia coli | 1 |
| 23571415 | 10.1124/mol.112.084152 | Solute carrier organic anion transporter family member 1B3 | 1 |
| 23571415 | 10.1124/mol.112.084152 | Solute carrier organic anion transporter family member 1B1 | 1 |
| 19642674 | 10.1021/jm900363q | Glutamate NMDA receptor | 1 |
| 18834112 | 10.1021/jm800656v | Amine oxidase [flavin-containing] B | 1 |
| 18834112 | 10.1021/jm800656v | Amine oxidase [flavin-containing] A | 1 |
| 12873507 | 10.1016/s0960-894x(03)00535-3 | Unchecked | 1 |
| 6094812 | 10.1021/jm00378a021 | ADMET | 1 |
Data from ChEMBL 36 via Core Engine