Compound Detail
CHEMBL296977
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Basic Information
| ChEMBL ID | CHEMBL296977 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LMJQHDOSKSGDCE-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
336.5
MW (Da)
5.17
ALogP
4
HBA
1
HBD
42.7
PSA (Ų)
0.65
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.96
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 CHEMBL4649 | IC50 | 6.96 | 6.96 | 110.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Corticotropin-releasing factor receptor 1 | IC50 | = | 110.0 | nM | 6.96 | Inhibition of binding of 70 pM [125I]-Try0-o-Corticotropin-releasing Factor (CFR... | 9171885 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9171885 | 10.1021/jm960861b | Corticotropin-releasing factor receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine