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Compound Detail

CHEMBL299842

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Nc1nc(O)cc(Nc2ccc(F)c(F)c2)n1
ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID CHEMBL299842
Phase Preclinical
Structure Type MOL
InChI Key KUTSIRBIGZNIFG-UHFFFAOYSA-N
0
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names

Molecular Properties

238.2
MW (Da)
1.79
ALogP
5
HBA
3
HBD
84.1
PSA (Ų)
0.74
QED
0
Ro5 Violations
2
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C10H8F2N4O
MW 238.20
Aromatic Rings 2
Heavy Atoms 17
NP-Likeness -1.96

Activity Summary

IC50 1 meas.

Literature References

PubMed DOI Target Context # Activities
7752205 10.1021/jm00010a026 HEL 2

Data from ChEMBL 36 via Core Engine