Compound Detail
CHEMBL303661
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL303661 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CJBSSFSBUKZFOW-AMIUJLCOSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
324.4
MW (Da)
1.47
ALogP
4
HBA
4
HBD
92.4
PSA (Ų)
0.54
QED
0
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 6.66
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.66 | 5.83 | 220.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 220.0 | nM | 6.66 | Inhibition of partially purified soluble aminopeptidase from rat brain | 3184127 |
| Unchecked | IC50 | = | 10000.0 | nM | 5.0 | Inhibition of partially purified soluble aminopeptidase from rat brain | 3184127 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 3184127 | 10.1021/jm00119a023 | Unchecked | 2 |
Data from ChEMBL 36 via Core Engine