Compound Detail
CHEMBL304865
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Basic Information
| ChEMBL ID | CHEMBL304865 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FKSYMILUYVSIDD-KGLIPLIRSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
267.4
MW (Da)
2.65
ALogP
2
HBA
1
HBD
46.2
PSA (Ų)
0.91
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.26
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor 4 CHEMBL3190 | EC50 | 6.26 | 6.26 | 551.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor 4 | EC50 | = | 551.0 | nM | 6.26 | Potentiation of responses mediated by 100 uM L-glutamate in transfected HEK293 c... | 11985477 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11985477 | 10.1021/jm0105474 | Glutamate receptor 4 | 2 |
Data from ChEMBL 36 via Core Engine