Compound Detail
CHEMBL307006
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Basic Information
| ChEMBL ID | CHEMBL307006 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PFMMKGGPOLDMEE-XRMCMGSZSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
344.6
MW (Da)
6.51
ALogP
1
HBA
1
HBD
20.2
PSA (Ų)
0.46
QED
1
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.36
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Aromatase CHEMBL1978 | Ki | 7.36 | 7.36 | 44.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Aromatase | Ki | = | 44.0 | nM | 7.36 | Apparent inhibition constant (Ki) against Cytochrome P450 19A1 | 8667367 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8667367 | 10.1021/jm960047o | Aromatase | 3 |
Data from ChEMBL 36 via Core Engine