Compound Detail
CHEMBL3084393
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Basic Information
| ChEMBL ID | CHEMBL3084393 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AMCQLHFZSJNRGF-ACDBMABISA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
307.4
MW (Da)
3.80
ALogP
2
HBA
1
HBD
23.5
PSA (Ų)
0.93
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M3 CHEMBL245 | IC50 | 5.82 | 5.82 | 1498.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M3 | IC50 | = | 1498.0 | nM | 5.82 | Antagonist activity against human M3 receptor expressed in CHO cells assessed as... | 19630384 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 19630384 | 10.1021/jm900736e | Muscarinic acetylcholine receptor M3 | 1 |
Data from ChEMBL 36 via Core Engine