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Compound Detail

CHEMBL3092230

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CC(=O)OCC1=C(C)C[C@H]([C@@H](C)[C@H]2CC[C@H]3[C@@H]4C[C@@H](O)C5=CC=CC(=O)[C@]5(COC(C)=O)[C@H]4CC[C@]23C)OC1=O

Basic Information

ChEMBL ID CHEMBL3092230
Phase Preclinical
Structure Type MOL
InChI Key YDYNWFXKODBECJ-IXVKYPSNSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
4
Publications
0
Known Names

Molecular Properties

554.7
MW (Da)
4.26
ALogP
8
HBA
1
HBD
116.2
PSA (Ų)
0.38
QED
1
Ro5 Violations
6
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C32H42O8
MW 554.68
Aromatic Rings 0
Heavy Atoms 40
NP-Likeness 2.74

Literature References

PubMed DOI Target Context # Activities
24273633 10.1021/ml400267q NON-PROTEIN TARGET 2
24273633 10.1021/ml400267q MRC5 1
24273633 10.1021/ml400267q SK-MEL-28 1
24273633 10.1021/ml400267q MDA-MB-231 1

Data from ChEMBL 36 via Core Engine