Compound Detail
CHEMBL3115317
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Basic Information
| ChEMBL ID | CHEMBL3115317 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JFIYEJVZMQCXMF-UHFFFAOYSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
345.3
MW (Da)
-0.14
ALogP
9
HBA
1
HBD
121.3
PSA (Ų)
0.70
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 7.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Transmembrane prolyl 4-hydroxylase CHEMBL3047 | IC50 | 7.16 | 7.16 | 70.0 | 1 |
| Unchecked CHEMBL612545 | IC50 | 7.16 | 7.16 | 70.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 70.0 | nM | 7.16 | Inhibition of prolyl hydroxylase (unknown origin) using biotin-labeled DLDLEMLAP... | 23977883 |
| Transmembrane prolyl 4-hydroxylase | IC50 | = | 70.0 | nM | 7.16 | In Vitro Inhibition Assay: In vitro tests for determination of the activity and ... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23977883 | 10.1021/jm400386j | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine