Compound Detail
CHEMBL3125370
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Basic Information
| ChEMBL ID | CHEMBL3125370 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | KVOXCWBRLIEGAY-FSPLNVSGSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
355.2
MW (Da)
2.38
ALogP
2
HBA
3
HBD
65.1
PSA (Ų)
0.58
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glycogen synthase kinase-3 beta CHEMBL262 | IC50 | 8.3 | 8.3 | 5.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glycogen synthase kinase-3 beta | IC50 | = | 5.0 | nM | 8.3 | Inhibition of GSK3beta (unknown origin) | 24560539 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24560539 | 10.1016/j.bmcl.2014.01.078 | Glycogen synthase kinase-3 beta | 1 |
| 24560539 | 10.1016/j.bmcl.2014.01.078 | Fibroblast | 1 |
Data from ChEMBL 36 via Core Engine