Compound Detail
CHEMBL316184
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Basic Information
| ChEMBL ID | CHEMBL316184 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UVEUKSMEMNIKBS-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
471.0
MW (Da)
6.41
ALogP
4
HBA
1
HBD
64.3
PSA (Ų)
0.30
QED
1
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 8.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Prostaglandin G/H synthase (cyclooxygenase) CHEMBL2111349 | IC50 | 8.4 | 8.4 | 4.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Prostaglandin G/H synthase (cyclooxygenase) | IC50 | = | 4.0 | nM | 8.4 | The compound was tested for inhibitory activity against Prostaglandin G/H syntha... | 1635053 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 1635053 | 10.1021/jm00092a001 | Prostaglandin G/H synthase (cyclooxygenase) | 1 |
Data from ChEMBL 36 via Core Engine