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Compound Detail

CHEMBL319256

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CC(C)CC[C@H](NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](NC(=O)[C@@H](N)CC(=O)O)[C@@H](C)O)C(C)C)C(N)=O

Basic Information

ChEMBL ID CHEMBL319256
Phase Preclinical
Structure Type BOTH
InChI Key BYUHQCHCIBRILN-MGHFTIBRSA-N
0
Targets
0
Activities
0
Assay Types
1
PK Parameters
2
Publications
0
Known Names

Molecular Properties

816.0
MW (Da)
-0.94
ALogP
10
HBA
11
HBD
317.0
PSA (Ų)
0.06
QED
2
Ro5 Violations
24
Rot. Bonds

Drug Information

Molecule Type Protein
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C39H61N9O10
MW 815.97
Aromatic Rings 2
Heavy Atoms 58
NP-Likeness 0.09

Pharmacokinetic Data

Parameter Value Units Species
KA 941.0 nm -

Literature References

PubMed DOI Target Context # Activities
10425111 10.1021/jm9807151 Substance-K receptor 2
10425111 10.1021/jm9807151 ADMET 1

Data from ChEMBL 36 via Core Engine