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Compound Detail

CHEMBL31962

BUTYL BORONIC ACID
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Basic Information

ChEMBL ID CHEMBL31962
Name BUTYL BORONIC ACID
Phase Preclinical
Structure Type MOL
InChI Key QPKFVRWIISEVCW-UHFFFAOYSA-N
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names

Molecular Properties

101.9
MW (Da)

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C4H11BO2
MW 101.94

Activity Summary

Ki 2 meas. best 5.0

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Aminopeptidase N
CHEMBL1907
Ki 5.0 5.0 10000.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Aminopeptidase N Ki = 10000.0 nM 5.0 Inhibition of AAP 19822427

Literature References

PubMed DOI Target Context # Activities
- 10.1016/S0960-894X(00)80519-3 Unchecked 1
9804697 10.1021/jm980343w Beta-lactamase 1
19822427 10.1016/j.bmcl.2009.09.077 Succinyl-diaminopimelate desuccinylase 1
19822427 10.1016/j.bmcl.2009.09.077 Aminopeptidase N 1

Data from ChEMBL 36 via Core Engine