Compound Detail
CHEMBL3197745
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Basic Information
| ChEMBL ID | CHEMBL3197745 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | PBEIAQYKTXKQGF-CXUHLZMHSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
369.2
MW (Da)
2.78
ALogP
4
HBA
2
HBD
78.8
PSA (Ų)
0.64
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RNA-binding protein 39 CHEMBL4680031 | IC50 | 6.4 | 6.4 | 400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RNA-binding protein 39 | IC50 | = | 400.0 | nM | 6.4 | Inhibition of RBM39 (unknown origin) | 37984298 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 25127462 | 10.1016/j.bmc.2014.07.022 | Candida albicans | 1 |
| 25127462 | 10.1016/j.bmc.2014.07.022 | Nakaseomyces glabratus | 1 |
| 37984298 | 10.1016/j.ejmech.2023.115950 | RNA-binding protein 39 | 1 |
Data from ChEMBL 36 via Core Engine