Compound Detail
CHEMBL3217774
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Basic Information
| ChEMBL ID | CHEMBL3217774 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | FOLYTFBHRHGMMG-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
413.2
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.72
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Vascular endothelial growth factor receptor 2 CHEMBL279 | IC50 | 6.72 | 6.72 | 190.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Vascular endothelial growth factor receptor 2 | IC50 | = | 190.0 | nM | 6.72 | Inhibition of KDR catalytic domain (unknown origin) assessed as reduction of pol... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1039/C0MD00115E | Epidermal growth factor receptor | 5 |
| - | 10.1039/C0MD00115E | Receptor tyrosine-protein kinase erbB-2 | 2 |
| - | 10.1039/C0MD00115E | Vascular endothelial growth factor receptor 1 | 2 |
| - | 10.1039/C0MD00115E | Vascular endothelial growth factor receptor 2 | 2 |
Data from ChEMBL 36 via Core Engine