Compound Detail
CHEMBL3221199
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL3221199 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DFGYYJBCGOVQHP-UYRXBGFRSA-N |
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
398.9
MW (Da)
4.99
ALogP
4
HBA
0
HBD
41.9
PSA (Ų)
0.68
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 5.67
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cannabinoid receptor 1 CHEMBL218 | Ki | 5.67 | 5.67 | 2160.0 | 1 |
| Cannabinoid receptor 1 CHEMBL3571 | Ki | 5.61 | 5.61 | 2460.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cannabinoid receptor 1 | Ki | = | 2160.0 | nM | 5.67 | Displacement of [3H]CP55,940 from human recombinant CB1 receptor expressed in CH... | - |
| Cannabinoid receptor 1 | Ki | = | 2460.0 | nM | 5.61 | Displacement of [3H]CP55,940 from CB1 receptor in rat brain cortical membranes | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1039/C3MD00394A | Cannabinoid receptor 1 | 4 |
| - | 10.1039/C3MD00394A | G-protein coupled receptor 35 | 4 |
| - | 10.1039/C3MD00394A | Cannabinoid receptor 2 | 3 |
| - | 10.1039/C3MD00394A | G-protein coupled receptor 55 | 3 |
| - | 10.1039/C3MD00394A | N-arachidonyl glycine receptor | 3 |
Data from ChEMBL 36 via Core Engine