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Compound Detail

CHEMBL3233722

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CC1(C)CC[C@]23CC[C@]4(C)[C@H](CC[C@@H]5[C@@]6(C)CC(N=[N+]=[N-])C(=O)C(C)(C)[C@@H]6CC[C@]54C)[C@H]2[C@H]1OC3

Basic Information

ChEMBL ID CHEMBL3233722
Phase Preclinical
Structure Type MOL
InChI Key NSDIZOKTWQNDPO-RGEODBJDSA-N
0
Targets
0
Activities
0
Assay Types
0
PK Parameters
6
Publications
0
Known Names

Molecular Properties

481.7
MW (Da)
7.73
ALogP
3
HBA
0
HBD
75.1
PSA (Ų)
0.22
QED
1
Ro5 Violations
1
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C30H47N3O2
MW 481.73
Aromatic Rings 0
Heavy Atoms 35
NP-Likeness 3.01

Literature References

PubMed DOI Target Context # Activities
24694263 10.1021/np400947d NON-PROTEIN TARGET 2
24694263 10.1021/np400947d NCI-H460 1
24694263 10.1021/np400947d DU-145 1
24694263 10.1021/np400947d MCF7 1
24694263 10.1021/np400947d SF-268 1
27236068 10.1016/j.ejmech.2016.05.029 NON-PROTEIN TARGET 1

Data from ChEMBL 36 via Core Engine