Compound Detail
CHEMBL3236579
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Basic Information
| ChEMBL ID | CHEMBL3236579 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OSRIFGUDXAOACA-BCFZYGEVSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
327.5
MW (Da)
2.32
ALogP
5
HBA
2
HBD
67.1
PSA (Ų)
0.89
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 8.77
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Histamine H4 receptor CHEMBL3759 | Ki | 8.77 | 8.77 | 1.7 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Histamine H4 receptor | Ki | = | 1.7 | nM | 8.77 | Displacement of [3H]histamine from human recombinant histamine H4 receptor expre... | 24495018 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24495018 | 10.1021/jm401727m | Histamine H4 receptor | 3 |
Data from ChEMBL 36 via Core Engine