Compound Detail

CHEMBL3250674

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O=C(O)CCCC[P+](c1ccccc1)(c1ccccc1)c1ccccc1.[Br-]

ChEMBL ↗ Properties Compare Identifier

Basic Information

ChEMBL ID	CHEMBL3250674
Phase	Preclinical
Structure Type	MOL
InChI Key	MLOSJPZSZWUDSK-UHFFFAOYSA-N
Parent Compound	CHEMBL3306011
Active Moiety	CHEMBL3306011

Targets

Activities

Assay Types

PK Parameters

Publications

Known Names

363.4

MW (Da)

4.24

ALogP

HBA

HBD

37.3

PSA (Å²)

0.48

QED

Ro5 Violations

Rot. Bonds

First in Class Prodrug

IC50 4 meas.

PubMed	DOI	Target Context	# Activities
38096652	10.1016/j.ejmech.2023.115973	Staphylococcus aureus	4
33691167	10.1016/j.bmcl.2021.127912	OVCAR-3	4
38096652	10.1016/j.ejmech.2023.115973	Pseudomonas aeruginosa	2
38096652	10.1016/j.ejmech.2023.115973	Acinetobacter baumannii	2
29890389	10.1016/j.ejmech.2018.06.012	BEAS-2B	1
38096652	10.1016/j.ejmech.2023.115973	L02	1
35818137	10.1021/acs.jmedchem.2c00640	MDA-MB-231	1
35818137	10.1021/acs.jmedchem.2c00640	MCF7	1
35818137	10.1021/acs.jmedchem.2c00640	A549	1
35818137	10.1021/acs.jmedchem.2c00640	A-375	1
29890389	10.1016/j.ejmech.2018.06.012	Unchecked	1
533881	10.1021/jm00197a012	No relevant target	1
29890389	10.1016/j.ejmech.2018.06.012	NCI-H1650	1
29890389	10.1016/j.ejmech.2018.06.012	A-375	1
29890389	10.1016/j.ejmech.2018.06.012	MCF7	1
28671831	10.1021/acs.jmedchem.7b00679	K562	1
28671831	10.1021/acs.jmedchem.7b00679	HL-60	1
28671831	10.1021/acs.jmedchem.7b00679	ECa-109 cell line	1
28671831	10.1021/acs.jmedchem.7b00679	A549	1
28671831	10.1021/acs.jmedchem.7b00679	HepG2	1

Data from ChEMBL 36 via Core Engine