Compound Detail
CHEMBL325603
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Basic Information
| ChEMBL ID | CHEMBL325603 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UEYRRMVOMQCUML-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
342.4
MW (Da)
2.40
ALogP
5
HBA
1
HBD
59.3
PSA (Ų)
0.91
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.44
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 4 CHEMBL2183 | EC50 | 6.44 | 6.44 | 360.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | EC50 | = | 360.0 | nM | 6.44 | Tested for ability to stimulate production of cAMP mediated by 5-hydroxytryptami... | 12540230 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12540230 | 10.1021/jm020099f | 5-hydroxytryptamine receptor 4 | 1 |
Data from ChEMBL 36 via Core Engine