Compound Detail
CHEMBL32609
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Basic Information
| ChEMBL ID | CHEMBL32609 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YQDDNXJWJDQWEC-WGOQTCKBSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
430.4
MW (Da)
5.47
ALogP
3
HBA
0
HBD
34.7
PSA (Ų)
0.26
QED
1
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 5.22
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M2 CHEMBL4781 | EC50 | 5.22 | 5.22 | 6000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Muscarinic acetylcholine receptor M2 | EC50 | = | 6000.0 | nM | 5.22 | Reduction of dissociation rate of [3H]N-methylscopolamine ([3H]NMS) from muscari... | 8182702 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8182702 | 10.1021/jm00036a008 | Muscarinic acetylcholine receptor M2 | 2 |
| 8182702 | 10.1021/jm00036a008 | No relevant target | 1 |
Data from ChEMBL 36 via Core Engine