Compound Detail
CHEMBL3263908
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Basic Information
| ChEMBL ID | CHEMBL3263908 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RQVYYZYZNCIRNR-RMORIDSASA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
397.4
MW (Da)
5.03
ALogP
5
HBA
2
HBD
71.7
PSA (Ų)
0.48
QED
1
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.58
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.58 | 5.58 | 2600.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 2600.0 | nM | 5.58 | Inhibition of HCV J4 genotype 1b NS5Bdelta21 polymerase using homopolymeric RNA ... | 24835816 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 24835816 | 10.1016/j.ejmech.2014.04.005 | Unchecked | 2 |
| 38109811 | 10.1016/j.bmc.2023.117559 | Unchecked | 2 |
| 38109811 | 10.1016/j.bmc.2023.117559 | Metallo-beta-lactamase type 2 | 1 |
Data from ChEMBL 36 via Core Engine