Compound Detail
CHEMBL326532
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Basic Information
| ChEMBL ID | CHEMBL326532 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RHYIUHUONWWZJC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
582.9
MW (Da)
7.39
ALogP
6
HBA
2
HBD
77.0
PSA (Ų)
0.11
QED
2
Ro5 Violations
27
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.48
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.48 | 6.48 | 331.1 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 331.13 | nM | 6.48 | Antagonist activity against Nicotinic acetylcholine receptor (nAChR) of isolated... | 12109912 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12109912 | 10.1021/jm020835f | Unchecked | 1 |
| 12109912 | 10.1021/jm020835f | Acetylcholine receptor subunit delta | 1 |
Data from ChEMBL 36 via Core Engine